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Sources of bias in observational studies of covid-19 vaccine effectiveness
In other words, 90%+ COVID "vaccine" efficacy claims are all bogus.
Discussion of multiple factors that can bias estimates of covid-19 vaccine effectiveness, such as:
vaccination status misclassification;
testing differences; and
disease risk factor confounding.
Our article complements these observations by providing examples based on actual data sets that quantify how case-counting window bias, age bias, and background infection rate bias can profoundly complicate the analysis of observational studies, shifting covid-19 vaccine effectiveness estimates by an absolute magnitude as high as 50% to 70%.
First published: 26 March 2023